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OCR: ed by the Hypopituitarism is most commonly cau The presence of a pituitary tumour (Fig. 2.2) ently tumour is usually benign and most freq reinoma is arises from the anterior lobe. Pituitary c tases occur very rare indeed, but in such cases meta inside or outside the nervous system. nd may Pituitary tumours range widely in size a press extend outside the pituitary fossa to com surrounding structures, Hypopituitarism can occur as a result of mal gland compression of secretory cells in the nor g tumours by a pituitary tumour. Large nonsecretir ressing the may also cause hypopituitarism by com elivery of pituitary stalk and interfering with the c pituitary. If hypothalamic hormones to the anterior this way, dopamine secretion is interfered with ir hyperprolactinaemia may ensue.